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Diffuse large B-cell lymphoma initially presenting with peritoneal dissemination.

Risa Hirata1, Masaki Tago1, Yoshinori Tokushima1

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A 62-year-old woman presented with abdominal distension and was diagnosed with diffuse large B-cell lymphoma. Imaging revealed extensive abdominal masses, confirmed by biopsy.

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Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Abdominal distension can indicate advanced malignancy.
  • Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma.
  • Early diagnosis is crucial for effective lymphoma treatment.

Purpose of the Study:

  • To report a case of diffuse large B-cell lymphoma presenting with extensive abdominal masses.
  • To highlight the role of imaging and biopsy in diagnosing intra-abdominal lymphoma.

Main Methods:

  • A 62-year-old female patient presented with severe abdominal distension.
  • Computed tomography (CT) with contrast enhancement was performed.
  • Ultrasound-guided needle biopsy confirmed the diagnosis.

Main Results:

  • CT revealed multiple, fused, homogeneously enhancing masses throughout the abdominal cavity.
  • No superficial lymphadenopathy was noted.
  • Histopathological examination confirmed diffuse large B-cell lymphoma.

Conclusions:

  • Diffuse large B-cell lymphoma can present with extensive intra-abdominal disease.
  • CT imaging is valuable for detecting widespread abdominal masses.
  • Ultrasound-guided biopsy is an effective method for diagnosing lymphoma in challenging cases.