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Updated: Oct 9, 2025

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Repeated adrenaline requirements for anaphylaxis
Josh Chatelier1, Stephanie Stojanovic1, Tiffany Lin1
1Allergy, Asthma and Clinical Immunology, Alfred Health, Melbourne, Victoria, Australia.
Abstract:
We examined the pattern of adrenaline administration in patients presenting with anaphylaxis. Forty-four percent required repeated adrenaline administration, among whom there had been greater cardiorespiratory compromise. Repeated administration was more frequent in males and older patients, and those triggered by insect sting or unknown cause; no other patient factors were identified. This study supports the provision of two adrenaline auto-injectors to all anaphylaxis patients.
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