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A Radical-Free Approach to Teeth Whitening
Mauro Pascolutti1, Dileusa de Oliveira1
1Hismile Research Centre, 225-229 Burleigh Connection Rd., Burleigh Waters 4220, Australia.
Dentistry Journal
|December 23, 2021
Summary
A new phthalimidoperoxycaproic acid (PAP) dental bleaching gel demonstrated superior safety and effectiveness compared to traditional hydrogen peroxide (HP) and carbamide peroxide (CP) agents in laboratory tests.
Area of Science:
- Dental materials science
- Biomaterials engineering
- Cosmetic dentistry
Background:
- Traditional dental bleaching agents like hydrogen peroxide (HP) and carbamide peroxide (CP) can cause adverse effects on hard and soft tissues.
- There is a need for safer and more effective dental bleaching alternatives.
Purpose of the Study:
- To evaluate the safety and effectiveness of a novel phthalimidoperoxycaproic acid (PAP) formulation with additives for dental bleaching.
- To compare the novel PAP+ gel against commercial HP and CP bleaching agents.
Main Methods:
- A new PAP+ gel was formulated and tested in laboratory settings.
- Effects on enamel surface profilometry and microhardness were assessed after six 10-minute exposures.
- In vitro effectiveness against polyphenol stains was compared to 6% HP.
Main Results:
- PAP+ gel did not cause enamel erosion, unlike HP gels.
- PAP+ gel preserved enamel surface microhardness, unlike both CP and HP gels.
- PAP+ gel showed superior stain removal compared to 6% HP, improving shade by approximately eight VITA shades.
Conclusions:
- The novel PAP+ formulation exhibits enhanced safety and effectiveness as a dental bleaching agent.
- PAP+ presents a promising alternative to traditional HP and CP bleaching agents.
- Laboratory findings support the clinical potential of PAP+ for safe and effective dental whitening.
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