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MoS2 Nanodonuts for High-Sensitivity Surface-Enhanced Raman Spectroscopy.

Samar Ali Ghopry1,2, Seyed M Sadeghi3, Cindy L Berrie4

  • 1Department of Physics and Astronomy, University of Kansas, Lawrence, KS 66045, USA.

Biosensors
|December 23, 2021
PubMed
Summary

Researchers developed novel molybdenum disulfide nanodonuts on graphene for enhanced Raman spectroscopy. This nanohybrid substrate achieves high sensitivity for biosensing applications.

Keywords:
TMD nanodonutsbiosensinggraphenenanohybridssurface-enhanced Raman spectroscopy

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Spectroscopy

Background:

  • Graphene and 2D transition metal dichalcogenides (TMD) nanostructures offer potential for surface-enhanced Raman spectroscopy (SERS).
  • The localized surface plasmonic resonance (LSPR) of TMD nanostructures is crucial for SERS enhancement, influenced by their morphology.
  • Existing SERS substrates often rely on plasmonic metals, limiting cost-effectiveness and sensitivity.

Purpose of the Study:

  • To report the first successful growth of molybdenum disulfide (MoS2) nanodonuts on graphene.
  • To investigate the SERS performance of MoS2 nanodonuts/graphene nanohybrids.
  • To demonstrate a novel non-metallic SERS substrate with high sensitivity.

Main Methods:

  • Vapor transport process for growing MoS2 nanodonuts on graphene.
  • Fabrication of MoS2 nanodonuts/graphene nanohybrid SERS substrates.
  • Surface-enhanced Raman spectroscopy (SERS) measurements using Rhodamine 6G (R6G) as a probe molecule.
  • Finite-difference time-domain (FDTD) simulations to analyze LSPR effects.

Main Results:

  • Successfully synthesized MoS2 nanodonuts on graphene substrates.
  • Achieved a remarkably high SERS sensitivity for R6G down to 2 × 10^-12 M.
  • Demonstrated a more robust LSPR effect in MoS2 nanodonuts compared to other nanostructures like nanodiscs.
  • Observed SERS sensitivity one order of magnitude higher than plasmonic metal-based SERS substrates.

Conclusions:

  • MoS2 nanodonuts/graphene nanohybrids represent a highly effective non-metallic SERS substrate.
  • The unique nanodonut morphology enhances LSPR, leading to superior SERS performance.
  • This approach offers a promising pathway for developing high-sensitivity, low-cost biosensing applications.