Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toward Long-Term Reliable Human-Machine Interaction: A Flexible, Breathable, and Self-Powered Pressure Sensor System With Firefighting Validation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

3D-Printed Gradient-Porous MXene@mRGO@SiO<sub>2</sub> Microspheres/SiC Hybrid Elastomer for Broadband Electromagnetic Wave Absorption.

Small methods·2025
Same author

Acetone Gas Sensors for Noninvasive Diabetes Diagnosis: A Comprehensive Review.

Chemical record (New York, N.Y.)·2025
Same author

Non-contact radiofrequency stimulation to the olfactory nerve of human subjects.

APL bioengineering·2025
Same author

Dynamic Growth Monitoring of <i>Saccharomyces cerevisiae</i> Based on Microwave Sensor Array.

ACS sensors·2025
Same author

Wireless Passive Flexible Radio Frequency Tactile Sensor for Material Recognition.

Nano letters·2025

Related Experiment Video

Updated: Oct 9, 2025

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

12.0K

Permittivity-Inspired Microwave Resonator-Based Biosensor Based on Integrated Passive Device Technology for Glucose

Wei Yue1, Eun-Seong Kim1, Bao-Hua Zhu1

  • 1Radio Frequency Integrated Circuit (RFIC), Kwangwoon University, Kwangwoon-ro, Nowon-gu, Seoul 01897, Korea.

Biosensors
|December 23, 2021
PubMed
Summary
This summary is machine-generated.

We developed a novel resonator biosensor for mediator-free glucose detection. This gallium arsenide (GaAs) device offers high sensitivity and a wide detection range, enabling reliable glucose monitoring.

Keywords:
air-bridge capacitorbiosensorglucose identificationintegrated passive device (IPD)microwavepermittivity

More Related Videos

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors
07:22

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Published on: November 20, 2013

17.1K
Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.6K

Related Experiment Videos

Last Updated: Oct 9, 2025

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

12.0K
Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors
07:22

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Published on: November 20, 2013

17.1K
Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.6K

Area of Science:

  • Electrical Engineering
  • Biomedical Engineering
  • Materials Science

Background:

  • Accurate glucose monitoring is crucial for diabetes management.
  • Existing biosensors often require mediators, adding complexity and potential error.
  • Development of sensitive, mediator-free biosensors is an ongoing research area.

Purpose of the Study:

  • To propose and characterize a high-performance resonator-based biosensor for mediator-free glucose identification.
  • To demonstrate the biosensor's capability for sensitive and reliable glucose detection.
  • To validate the biosensor's performance metrics, including sensitivity, detection range, and reusability.

Main Methods:

  • Fabrication of an air-bridge capacitor biosensor using integrated passive device technology on a gallium arsenide (GaAs) substrate.
  • Utilizing a spiral inductor with an air-bridge as the sensing surface.
  • Measuring resonant frequency shifts in response to varying glucose concentrations.
  • Analyzing surface morphology and chemical binding to confirm reusability.

Main Results:

  • The biosensor achieved resonant frequency shifts of 0.874 GHz and 1.244 GHz for glucose concentrations of 25 mg/dL and 300 mg/dL, respectively.
  • Demonstrated high sensitivity of 1.38 MHz/mg/dL within a wide detection range (25-300 mg/dL).
  • Achieved a low detection limit of 24.59 mg/dL with high linearity (R²=0.98823) and a rapid response time (<3 s).

Conclusions:

  • The proposed resonator-based biosensor offers a promising solution for mediator-free glucose identification.
  • The GaAs-based device exhibits excellent sensitivity, a broad detection range, and high reliability.
  • The biosensor's design and performance validate its potential for practical glucose monitoring applications.