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Updated: Oct 9, 2025
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Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
Published on: March 6, 2018
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Obesogens in Children-An Uncharted Territory
Mirjam Močnik1, Nataša Marčun Varda1,2
1Department of Paediatrics, University Medical Centre Maribor, Ljubljanska ulica 5, 2000 Maribor, Slovenia.
Metabolites
|December 23, 2021
Summary
Obesogens are chemicals that may cause obesity. Research on their effects in children is ongoing, with limited evidence and unknown mechanisms, highlighting the need for further study.
Area of Science:
- Environmental Health
- Endocrinology
- Pediatrics
Background:
- Obesogens are endocrine-disrupting chemicals linked to obesity development.
- Commonly studied obesogens in children include BPA, phthalates, PFAS, and POPs.
- Exposure can occur in utero and postnatally, with growing research interest.
Purpose of the Study:
- To review the current understanding of obesogens and their potential role in childhood obesity.
- To highlight the chemicals under investigation and their sources.
- To identify gaps in knowledge regarding mechanisms and human effects.
Main Methods:
- Literature review of existing studies on obesogen exposure and childhood obesity.
- Analysis of associations between prenatal and postnatal chemical exposure.
- Examination of proposed mechanisms of action for various obesogenic substances.
Main Results:
- The obesogen theory is considered plausible by many researchers.
- Inconsistent evidence supports the obesogenic effects of most studied chemicals in children.
- Exact mechanisms of action and combined effects in humans, especially children, remain largely unknown.
Conclusions:
- Current data on obesogens in children are limited, indicating a need for more research.
- Understanding obesogen impact is crucial for public health policy and intervention.
- Further investigation is required to elucidate obesogen mechanisms and mitigate risks.
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