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Updated: Oct 9, 2025
Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
Published on: July 12, 2018
[Loop colostomy as a risk factor of postoperative ileus in elective colorectal cancer surgery]
D A Khubezov1, V P Sazhin1, I S Ignatov2
1Ryazan State Medical University, Ryazan, Russia.
Objective:
To identify risk factors of postoperative ileus (POI) in elective colorectal cancer (CRC) surgery.
Material And Methods:
A non-randomized retrospective study included 220 patients who underwent elective surgery for colorectal tumors. The indication for surgery was CRC stage 0-IV in 213 (96.8%) cases, villous adenoma in 7 cases (3.2%). Risk factors of POI defined in univariate analysis were included into multivariate analysis. Logistic regression was used in this case.
Results:
Risk factors of POI were male sex (p=0.04), multifocal CRC (p=0.03), intraoperative transfusion (p=0.005), postoperative transfusion (p=0.035), left-sided hemicolectomy (p=0.01), colostomy (p=0.02), loop transversostomy (p=0.003), loop colostomy (p=0.02). According to logistic regression, independent risk factors of POI were male sex (p=0.015), left-sided hemicolectomy (p=0.004), intraoperative transfusion p=0.002), loop transversostomy (p=0.019).
Conclusion:
Independent risk factors of POI in elective colorectal cancer surgery were male sex, left-sided hemicolectomy, intraoperative transfusion and loop transversostomy.
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