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Overdose of Quetiapine-A Case Report with QT Prolongation
Elisabetta Bertol1, Fabio Vaiano2, Antonina Argo3
1Research Unit U.R.I.To.N., University of Firenze, 50134 Firenze, Italy.
Abstract:
Quetiapine is an atypical antipsychotic drug used to treat bipolar disorder, schizophrenia, and major depressive disorder. Although several studies describe the adverse effects of intoxication with Quetiapine, only a few report an extreme overdose without comedications that lead to a life threat. We present a case of a 75-year-old male who tried to attempt suicide by ingesting 28 g of Quetiapine. During the management in the emergency department, both serum and urine samples were collected, allowing a complete pharmacokinetic analysis to be conducted, from the admission to the discharge.
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