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Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...

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Related Experiment Video

Updated: Oct 9, 2025

Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis

Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis

Published on: November 14, 2016

Multiple sclerosis in 2021: progress against progression

Erin S Beck¹, Daniel S Reich²

¹Icahn School of Medicine at Mount Sinai, New York, NY, USA.

The Lancet. Neurology

|December 23, 2021

Summary

No abstract available in PubMed .

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