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Accessory Structures of the Skin: Hair Growth and Types01:20

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Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
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Transient fetal hypertrichosis - Three cases.

M Bronshtein1, Nguyen To Hac2, A Gover3

  • 1Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel; Faculty of Social Welfare & Health Sciences, University of Haifa, Haifa, Israel.

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|December 23, 2021
PubMed
Summary
This summary is machine-generated.

Transient fetal hypertrichosis, or excessive hair growth, in low-risk pregnancies is rare but typically resolves. This condition, noted on prenatal ultrasounds, often indicates a favorable prenatal outcome.

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Area of Science:

  • Obstetrics and Gynecology
  • Prenatal Diagnostics
  • Medical Genetics

Background:

  • Transient fetal hypertrichosis is infrequently documented in prenatal ultrasound reports.
  • Historically, hypertrichosis has been linked to over 140 genetic syndromes (OMIM).
  • This study focuses on three cases of transient fetal hypertrichosis in low-risk pregnancies.

Discussion:

  • The presence of fetal hypertrichosis on prenatal scans, even with associated findings like horseshoe kidney, may not indicate adverse outcomes.
  • The observed hypertrichosis resolved later in gestation across all cases.
  • Localized hypertrichosis, such as synophrys (unibrow) or hair on the back or chin, can be transient.

Key Insights:

  • Transient, localized fetal hypertrichosis without other major anomalies is associated with a favorable prenatal prognosis.
  • Early identification via ultrasound allows for monitoring and reassurance.
  • This finding highlights the importance of considering benign causes for fetal hypertrichosis.

Outlook:

  • Further research is warranted to understand the specific mechanisms behind transient fetal hypertrichosis.
  • Establishing clear diagnostic criteria for benign fetal hypertrichosis can reduce unnecessary anxiety and interventions.
  • Continued surveillance of these cases will confirm long-term outcomes.