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Updated: Oct 9, 2025

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Extraction of Venom and Venom Gland Microdissections from Spiders for Proteomic and Transcriptomic Analyses
Published on: November 3, 2014
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Venomous Snake and Spider Bites in Pregnancy
Emily Chen1, Sarah Dotters-Katz2, Jeffrey A Kuller3
1Medical Student, Duke University School of Medicine.
Obstetrical & Gynecological Survey
|December 23, 2021
Summary
Venomous snake and spider bites during pregnancy are rare but serious. Antivenom therapy is likely safe for pregnant patients with proper monitoring, though more research is needed.
Area of Science:
- Toxicology
- Emergency Medicine
- Obstetrics
Background:
- Venomous snake and spider bites (envenomations) are uncommon in pregnant individuals in the U.S.
- Envenomations can pose significant risks to both maternal and fetal health.
- Healthcare providers in high-risk areas need specialized knowledge for managing these cases.
Purpose of the Study:
- To review common U.S. snake and spider envenomations.
- To examine the effects of envenomation on pregnant patients and fetuses.
- To outline management strategies for envenomation during pregnancy.
Main Methods:
- Literature review of original research, review articles, and guidelines.
- Focused on snake and spider envenomations in the United States.
- Analysis of maternal and fetal outcomes and treatment efficacy.
Main Results:
- Snake envenomations present higher maternal and fetal morbidity/mortality risks than spider envenomations.
- Limited data suggest snake and spider antivenoms are generally safe in pregnancy.
- Potential hypersensitivity reactions to antivenom require careful risk-benefit assessment.
Conclusions:
- Antivenom therapy for symptomatic pregnant patients is likely safe with appropriate monitoring.
- Understanding indications for antivenom and care escalation is crucial for optimal outcomes.
- Further research is necessary to fully elucidate the effects of envenomation and antivenom on pregnancy.
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