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Urethral trichomoniasis in men.

A S Latif, P R Mason, E Marowa

    Sexually Transmitted Diseases
    |January 1, 1987
    PubMed
    Summary
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    Urethral trichomoniasis in men presents with prolonged discharge and irritation. A five-day course of metronidazole effectively cures this sexually transmitted infection in 100% of cases.

    Area of Science:

    • Urology
    • Infectious Diseases
    • Parasitology

    Background:

    • Urethral trichomoniasis is a sexually transmitted infection affecting men.
    • Symptoms often include prolonged urethral discharge and irritation, distinguishing it from other urethritis causes.

    Purpose of the Study:

    • To describe the clinical presentation and diagnostic findings of urethral trichomoniasis in men.
    • To evaluate the efficacy of different metronidazole treatment regimens for male trichomoniasis.

    Main Methods:

    • Retrospective analysis of 325 men diagnosed with urethral trichomoniasis at STD clinics in Harare, Zimbabwe (1983-1984).
    • Clinical data collection on symptoms, duration, discharge characteristics, and microscopy findings.
    • Microscopic examination of urethral secretions and urine sediment; bacterial culture of urethral exudates.
    Keywords:
    AfricaAfrica South Of The SaharaAge FactorsAntibiotics--administraction and dosageBiologyClinical ResearchDemographic FactorsDeveloping CountriesDiseasesDrugsEastern AfricaEnglish Speaking AfricaExaminations And DiagnosesInfectionsLaboratory Examinations And DiagnosesMeasurementPhysiologyPopulationPopulation CharacteristicsPrevalenceReproductive Tract InfectionsResearch MethodologySexually Transmitted DiseasesSigns And SymptomsTreatmentUrogenital Effects--menUrogenital SystemZimbabwe

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  • Evaluation of treatment outcomes for single-dose versus multi-day metronidazole regimens.

    • Main Results:

    • The mean age of patients was 30.4 years, with common symptoms of urethral discharge and irritation lasting over four weeks in 78% of cases.
    • Discharge was typically milky white and fluid; microscopy revealed few polymorphonuclear leukocytes and many epithelial cells.
    • Trichomonas vaginalis was identified via microscopy in urethral secretions and urine, but only cultured from urethral exudates.
    • A single 2g dose of metronidazole had a 42.9% failure rate, while a 5-day regimen (400mg TID) achieved a 100% cure rate.

    Conclusions:

    • Urethral trichomoniasis in men is characterized by persistent symptoms and specific discharge characteristics.
    • Multi-day metronidazole therapy is highly effective for treating male trichomoniasis, unlike single-dose regimens.