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The Use of Auto-Titrating Continuous Positive Airway Pressure (AutoCPAP) for Obstructive Sleep Apnea Syndrome in

Sarah Benke1, Caroline U A Okorie2, MaryAnne A Tablizo2,3

  • 1Department of Pediatrics, Valley Children's Hospital, Madera, CA 93636, USA.

Children (Basel, Switzerland)
|December 24, 2021
PubMed

Insights

Auto-adjusting positive airway pressure (autoCPAP) is a safe and effective treatment for children with obesity and obstructive sleep apnea syndrome (OSAS). This therapy significantly reduced apnea events, showing promise for timely intervention.

Area of Science:

  • Pediatric Pulmonology
  • Sleep Medicine
  • Obesity Medicine

Background:

  • Obstructive Sleep Apnea Syndrome (OSAS) affects children, with positive airway pressure therapy being a common treatment.
  • Limited research exists on the efficacy and safety of auto-adjusting positive airway pressure (autoCPAP) in obese pediatric populations.

Purpose of the Study:

  • To evaluate the safety and effectiveness of autoCPAP in treating pediatric patients with obesity and OSAS.
  • To compare autoCPAP adherence and pressure settings with traditional PAP titration.

Main Methods:

  • Retrospective chart review of children (ages 2-18) with obesity (BMI > 99th percentile) diagnosed with OSAS.
  • Analysis of 30-day autoCPAP adherence and comparison of baseline Obstructive Apnea-Hypopnea Index (OAHI) with post-treatment AHI.
  • Comparison of autoCPAP 95th percentile pressures with PAP titration pressures.

Main Results:

  • 19 children (ages 5-15) with a median BMI of 99.6th percentile were included.
  • Average autoCPAP adherence was 25/30 nights, with a mean use of 7.3 hours/night.
  • Median OAHI decreased from 12.3/h to 1.7/h, with no reported adverse outcomes. AutoCPAP pressures closely matched PAP titration pressures.

Conclusions:

  • AutoCPAP appears to be an effective and safe treatment for OSAS in pediatric patients with obesity.
  • This therapy may expedite treatment initiation for this population.
  • Further research is warranted to confirm long-term autoCPAP effectiveness in pediatric obesity.
Abstract

Keywords:
auto-titrating continuous positive airway pressureobesityobstructive sleep apneapediatric sleep apneapositive airway pressuresleep disordered breathing

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