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Case Series of Variable Acute Appendicitis in Children with SARS-CoV-2 Infection

Arnis Engelis1,2, Liene Smane3,4, Jana Pavare3,4

  • 1Department of Paediatric Surgery, Riga Stradins University, LV-1007 Riga, Latvia.

Children (Basel, Switzerland)
|December 24, 2021
PubMed

Insights

Six children with acute appendicitis were identified among 121 COVID-19 positive pediatric admissions. This suggests a potential link between SARS-CoV-2 infection and appendicitis in children, warranting further investigation.

Area of Science:

  • Pediatric Surgery
  • Infectious Diseases
  • Gastroenterology

Background:

  • The emergence of SARS-CoV-2 (the virus causing COVID-19) has presented unique challenges in pediatric healthcare.
  • Understanding the spectrum of COVID-19 complications in children is crucial for timely diagnosis and management.

Observation:

  • A case series identified six pediatric patients (aged 5-16) with acute appendicitis during a SARS-CoV-2 infection period.
  • These cases occurred within a cohort of 121 hospitalized COVID-19 positive children, with 40.5% presenting gastrointestinal symptoms.
  • Five patients underwent appendectomy, while one received conservative management.

Findings:

  • The study observed a plausible association between SARS-CoV-2 infection and acute appendicitis in the pediatric population.
  • Gastrointestinal symptoms in COVID-19 positive children may indicate underlying appendicitis.
  • Non-surgical treatment approaches for appendicitis might become more relevant in the context of COVID-19.

Implications:

  • Pediatric surgeons and healthcare providers should consider SARS-CoV-2 testing in children presenting with severe gastrointestinal symptoms.
  • The findings highlight the need for increased vigilance regarding acute abdominal conditions in pediatric COVID-19 patients.
  • Further research is required to establish a definitive causal relationship between COVID-19 and pediatric appendicitis.

Keywords:
COVID-19SARS-CoV-2paediatric abdominal painpaediatric appendicitis

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