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Extracellular Signalling Modulates Scar/WAVE Complex Activity through Abi Phosphorylation

Shashi Prakash Singh1, Peter A Thomason1, Robert H Insall1,2

  • 1CRUK Beatson Institute, Glasgow G61 1BD, UK.

Cells
|December 24, 2021
PubMed
Summary

Cell migration relies on the Scar/WAVE complex. In Dictyostelium, Abi subunit phosphorylation by extracellular signals fine-tunes pseudopod dynamics and cell speed after Scar/WAVE activation.

Keywords:
F-actinScar/WAVE complexmigrationphosphorylationpseudopodia

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