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Atherosclerosis III: Management01:26

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Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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The human body gets energy from the three macronutrients: carbohydrates, proteins, and fats. Energy is released when the chemical bonds in the organic compounds present in the food are broken down. The energy content of food is measured in kilocalories (kcal), defined as the amount of heat required to raise the temperature of one kilogram of water by one degree Celsius. This value is determined by measuring the temperature change of the water surrounding a calorimeter after the complete...
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Updated: Oct 9, 2025

Multidisciplinary Approach to Obesity Management: A Case Report
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Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

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Plant-Based Diet as a Strategy for Weight Control.

Stanislava Ivanova1, Cédric Delattre2,3, Diana Karcheva-Bahchevanska1

  • 1Department of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, 4002 Plovdiv, Bulgaria.

Foods (Basel, Switzerland)
|December 24, 2021
PubMed
Summary

Vegan diets show promise for weight control by improving gut health and insulin sensitivity. This plant-based approach reduces calorie density and cholesterol, offering an effective strategy for managing obesity.

Keywords:
globesityobesityobesity managementplant-based dietveganvegetarianweight controlweight loss

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Area of Science:

  • Nutrition Science
  • Public Health

Background:

  • Global obesity rates have nearly tripled since the 1970s, posing significant health risks including cardiovascular diseases, diabetes, and increased COVID-19 mortality.
  • Current weight management strategies have demonstrated limited efficacy.
  • Emerging research highlights the potential of plant-based diets for effective weight control.

Purpose of the Study:

  • To systematically review the scientific literature on the efficacy of vegan and plant-based diets for weight management.
  • To identify the key mechanisms through which these diets influence body weight and metabolic health.

Main Methods:

  • A systematic literature search was conducted across major scientific databases (PubMed, Web of Science, Scopus, Embase) adhering to PRISMA guidelines.
  • Keywords included "obesity", "globesity", "vegan", and "plant-based diet".

Main Results:

  • Vegan diets are associated with improved gut microbiota symbiosis and enhanced insulin sensitivity.
  • Activation of peroxisome proliferator-activated receptors and over-expression of mitochondrial uncoupling proteins were observed.
  • Key dietary features include reduced calorie density and cholesterol intake, contributing to weight loss efficacy.

Conclusions:

  • Plant-based and vegan diets offer a promising and effective strategy for reducing body weight.
  • The combination of reduced calorie density and cholesterol intake is central to the effectiveness of these diets.
  • Further integration of plant-based diets into weight management strategies is recommended.