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Mutagenicity and Carcinogenicity

Mutagenicity and Carcinogenicity

Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...

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Related Experiment Video

Updated: Oct 8, 2025

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

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Reply to: Prospects and challenges for FAIR toxicogenomics data

Roland Grafström^1,2, Andrea Haase³, Pekka Kohonen^1,2

¹Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.

Nature Nanotechnology

|December 24, 2021

Summary

No abstract available in PubMed .

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