Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical and metabolic factors associated with response to postoperative radioactive iodine therapy in Chinese obese patients with papillary thyroid carcinoma.

Frontiers in endocrinology·2026
Same author

Editorial: Gene editing in cancer gene therapy.

Frontiers in medicine·2026
Same author

Aliphatic Chain-Derived Fluorescein Aggregates for Surfactants Discrimination and CMC Determination.

Journal of fluorescence·2026
Same author

Single photon emission computed tomography/computed tomography clue to pulmonary metastasis in osteosarcoma: a diagnostic pitfall of technetium-99m methylene diphosphonate uptake.

Quantitative imaging in medicine and surgery·2026
Same author

Super-adhesive sensor based on amylopectin-polyacrylic acid hydrogel for deep learning-assisted sign language recognition.

Journal of colloid and interface science·2026
Same author

Brain-Directed AAV Gene Therapy Rescues a Mouse Model of the CLN5 Form of Neuronal Ceroid Lipofuscinosis Disease and Normalizes a Blood Plasma Biomarker of Neurodegeneration.

Human gene therapy·2025

Related Experiment Video

Updated: Oct 8, 2025

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
04:01

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Published on: September 15, 2023

1.0K

Risk Factor Analysis for Central Lymph Node Metastasis in Papillary Thyroid Microcarcinoma.

Wenfei Liu1, Shoufei Wang1, Xiaotian Xia1

  • 1Department of Thyroid, Parathyroid, Breast and Hernia Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, People's Republic of China.

International Journal of General Medicine
|December 24, 2021
PubMed
Summary

Cervical lymph node metastasis (CLNM) affects 17.6% of papillary thyroid microcarcinoma (PTMC) patients. Key risk factors for CLNM in PTMC include microcalcification, younger age, and tumor invasion.

Keywords:
ageinvasionmicrocalcificationpapillary thyroid microcarcinomarisk factors

More Related Videos

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
07:02

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice

Published on: August 23, 2019

7.5K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

664

Related Experiment Videos

Last Updated: Oct 8, 2025

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
04:01

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Published on: September 15, 2023

1.0K
In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
07:02

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice

Published on: August 23, 2019

7.5K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

664

Area of Science:

  • Endocrinology
  • Oncology
  • Surgical Pathology

Background:

  • Papillary thyroid microcarcinoma (PTMC) generally has an excellent prognosis.
  • Cervical lymph node metastasis (CLNM) is a frequent finding in PTMC.
  • Identifying risk factors for CLNM is crucial for tailoring treatment strategies.

Purpose of the Study:

  • To determine the incidence of CLNM in PTMC patients.
  • To investigate the clinicopathologic and ultrasound-related risk factors associated with CLNM in PTMC.

Main Methods:

  • A retrospective analysis of 687 PTMC patients who underwent thyroidectomy and lymph node dissection.
  • Patients were categorized into groups with and without CLNM.
  • Clinicopathologic characteristics and ultrasound features were compared.
  • Univariate and multivariate logistic regression analyses were performed to identify risk factors.

Main Results:

  • The overall incidence of CLNM in PTMC was 17.6% (121/687).
  • Significant risk factors identified by multivariate analysis included microcalcification (OR: 2.066), age <55 years (OR: 2.341), capsular invasion (OR: 1.772), and invasion of adjacent tissues (OR: 2.872).
  • Younger patients (<55 years) and those with capsular or adjacent tissue invasion showed higher rates of CLNM.

Conclusions:

  • Microcalcification on ultrasound, younger age (<55 years), capsular invasion, and invasion of adjacent tissues are significant predictors of CLNM in PTMC.
  • These findings can aid in risk stratification and personalized management of PTMC.