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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
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What an Interventionalist Needs to Know About INOCA

Daniel Tze Yee Ang1,2, Colin Berry1,2

  • 1University of Glasgow Glasgow, UK.

Interventional Cardiology (London, England)
|December 24, 2021
PubMed

Insights

Ischaemia with non-obstructed coronary artery disease (INOCA) presents diagnostic challenges. The interventional diagnostic procedure (IDP) helps differentiate INOCA types, improving patient quality of life through personalized care.

Area of Science:

  • Cardiology
  • Vascular Medicine

Background:

  • Ischaemia with non-obstructed coronary artery disease (INOCA) is a complex clinical challenge.
  • Traditional anatomical approaches overlook vasomotion disorders, a key factor in INOCA.
  • INOCA encompasses microvascular angina, vasospastic angina, and mixed or non-cardiac symptoms.

Purpose of the Study:

  • To review a stratified approach to diagnosing and managing INOCA.
  • To describe a streamlined interventional diagnostic procedure (IDP) for INOCA endotyping.
  • To highlight practical and safety considerations for IDP implementation.

Main Methods:

  • Utilizing the interventional diagnostic procedure (IDP) to differentiate INOCA endotypes.
  • Linking diagnostic findings to stratified medical therapy.
  • Reviewing current guidelines and clinical practice regarding coronary function tests.

Main Results:

  • The IDP allows for precise differentiation between INOCA clinical endotypes.
  • Stratified medical therapy based on IDP results reduces symptom burden.
  • Personalized care improves the quality of life for INOCA patients.

Conclusions:

  • The IDP is crucial for personalized management of INOCA.
  • Wider adoption of IDP in clinical practice is encouraged despite limited current use.
  • Interventionists can significantly impact patient outcomes through tailored INOCA care.

Keywords:
Ischaemia with no obstructive coronary artery diseaseanginacoronarycoronary microvascular dysfunctioninterventional diagnostic procedureischaemic heart diseasevasospastic angina

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