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Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

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Coronary Artery Disease in Chronic Kidney Disease: Need for a Heart-Kidney Team-Based Approach

Gautam R Shroff1, Michelle D Carlson1, Roy O Mathew2

  • 1Division of Cardiology, Department of Medicine, Hennepin Healthcare & University of Minnesota Medical School Minneapolis, MN, US.

European Cardiology
|December 24, 2021
PubMed

Insights

Patients with chronic kidney disease and coronary artery disease face high cardiovascular risks. A collaborative heart-kidney approach is crucial for managing coronary heart disease and revascularization decisions in this population.

Area of Science:

  • Cardiology
  • Nephrology
  • Internal Medicine

Background:

  • Chronic kidney disease (CKD) and coronary artery disease (CAD) frequently coexist.
  • This comorbidity significantly increases the risk of major adverse cardiovascular outcomes, including mortality.
  • Unique epidemiological and pathophysiological factors link CKD and CAD.

Purpose of the Study:

  • To review current literature on non-invasive risk assessment for patients with co-prevalent CKD and CAD.
  • To summarize medical management and coronary revascularization strategies for this population.
  • To propose an algorithm for revascularization decisions in end-stage kidney disease (ESKD) patients.

Main Methods:

  • Literature review summarizing existing research on CKD-CAD management.
  • Analysis of non-invasive risk assessment tools.
  • Evaluation of periprocedural considerations for coronary revascularization.
  • Development of a proposed decision-making algorithm.

Main Results:

  • CKD and CAD share complex pathophysiological links.
  • Non-invasive risk assessment requires careful consideration in this dual-disease state.
  • A collaborative, team-based approach is essential for optimal management.
  • Specific periprocedural strategies are vital for safe coronary revascularization.

Conclusions:

  • Integrated care models are necessary for managing patients with CKD and CAD.
  • Revascularization decisions in ESKD require a tailored, evidence-based approach.
  • Further research is needed to refine management strategies for this high-risk group.

Keywords:
Chronic kidney diseasecoronary artery bypass surgerycoronary artery diseasedialysisend-stage kidney diseasenon-invasive imagingpercutaneous coronary intervention

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