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Updated: Oct 8, 2025

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Published on: August 30, 2020
A case of malignant hypertension with multi-organ injury
Ikuo Misumi1, Mikiko Fukushima2, Kuniyasu Wada3
1Department of Cardiology, Kumamoto City Hospital, 4-1-60, Higashi-machi, Higashi-ku, Kumamoto City, Kumamoto 862-8505, Japan.
Abstract:
A 33-year-old woman visited our hospital due to visual loss. Her BP was 280/150 mm Hg and pulse rate was 111 beats per minute. A urinalysis showed protein in urine, suggesting kidney injury. A transthoracic echocardiography showed left ventricular hypertrophy. A Cardiac magnetic resonance imaging suggested left ventricular endocardial edema or inflammation. Ophthalmoscopy showed optic disc edema and hard exudates in both eyes. A brain MRI showed multiple high-intensity areas at the pons and white matter of the cerebrum and cerebellum. Although the patient had malignant hypertension, she was successfully treated by medication.
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