Nutritional ecology, infection and immune defence - exploring the mechanisms

Diet can impact the outcome of parasitic infection in three, non-mutually exclusive ways: 1) by changing the physiological environment of the host, such as the availability of key nutritional resources, the presence of toxic dietary chemicals, the pH or osmolality of the blood or gut, 2) by enhancing the immune response and 3) by altering the presence of host microbiota, which help to digest nutrients and are a potential source of antibiotics. We show that there are no clear patterns in the effects of diet across taxa and that good evidence for the mechanisms by which diet exerts its effects are often lacking. More studies are required to understand the mechanisms of action if we are to discern patterns that can be generalised across host and parasite taxa.