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Published on: September 20, 2024
Thyroidectomy practice in pediatric population: a national perspective
Zaid Al-Qurayshi1, Joseph D Peterson2, Mohamed A Shama3
1Department of Otolaryngology-Head & Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Insights
Pediatric thyroidectomy is most often for benign conditions, with higher costs and no improved outcomes at children's hospitals. Hypocalcemia is a common complication, especially in thyroid cancer cases.
Area of Science:
- Pediatric surgery
- Endocrinology
- Health services research
Background:
- Thyroidectomy is a common surgical procedure in pediatric patients.
- Understanding the epidemiology and outcomes of pediatric thyroidectomy is crucial for optimizing patient care.
- Previous studies have not comprehensively analyzed national trends in pediatric thyroidectomy.
Purpose of the Study:
- To examine the presentations and outcomes of pediatric patients undergoing thyroidectomy.
- To identify risk factors for postoperative complications.
- To compare outcomes and costs associated with management in children's hospitals versus general hospitals.
Main Methods:
- Retrospective cross-sectional analysis of the Nationwide Readmissions Database (2010-2014).
- Inclusion of pediatric patients (<18 years) undergoing thyroidectomy.
- Analysis of patient demographics, thyroid disease types, surgical procedures, complications, and healthcare costs.
Main Results:
- A total of 361 pediatric patients were analyzed, with a mean age of 13.5 years; 79.8% were female.
- The most common indications were non-toxic benign disease (42.0%) and toxic nodular disease (33.6%).
- Hypocalcemia was the most frequent complication (98.2% of complications), with higher risk in thyroid cancer and toxic thyroid disease cases. Management in children's hospitals was associated with significantly higher costs ($19,457.50 vs. $13,788.00) without improved outcomes.
Conclusions:
- Thyroidectomy in the pediatric population is predominantly performed for benign conditions.
- A significant proportion of pediatric thyroidectomies occur at low-volume centers.
- Management in children's hospitals incurs higher costs without demonstrable benefits in outcomes or hospital stay duration.
Purpose:
To examine presentations and outcomes of pediatric patients underoing thyroidectomy.
Materials And Methods:
A retrospective cross-sectional analysis of the Nationwide Readmissions Database, 2010-2014, was performed. Study population included pediatric (<18 years) inpatients undergoing thyroidectomy.
Results:
A total of 361 patients were included. Mean age was 13.5 ± 0.2 years, and 79.8% were female. Thyroid diseases included: (i) 19.0% thyroid cancer, (ii) 5.4% Multiple Endocrine Neoplasia type II, (iii) 33.6% toxic nodular disease, and (iv) 42.0% non-toxic benign disease. Total thyroidectomy was performed in 67.7% of the patients, and 3.2% of the patients who had initial lobectomy were readmitted within 3 months for completion thyroidectomy. Postoperative complications were reported in 14.2% of the sample, and hypocalcemia was the most common complication (98.2%). Risk of hypocalcemia was significantly higher in patients who had thyroid cancer (risk = 20.9%, p = 0.011) or toxic thyroid diseases (risk = 19.8%, p = 0.033). Of the study population, 25.6% were managed exclusively in children's hospitals. Management in children's hospitals was not associated with improved outcomes or shorter hospital stay; however, it was associated with a significantly higher cost of health services [US $19,4575.0 ± 195.49 vs. US $13,788.00 ± 238.51, p < 0.001].
Conclusions:
This study reports a national perspective on thyroidectomy in the pediatric population. Most thyroid surgeries performed in the pediatric population are performed for benign conditions. Most pediatric thyroidectomies are performed at low-volume centers. Surgeries performed in children's hospitals are significantly higher in cost without any associated improvement in outcomes or length of hospital stay.
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