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Updated: Oct 8, 2025
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Intravenous Endotoxin Challenge in Healthy Humans: An Experimental Platform to Investigate and Modulate Systemic Inflammation
Published on: May 16, 2016
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Impact of endotoxins on bioengineered tissues and models
Marcel A Heinrich1, Marina Mangia1, Jai Prakash1
1Engineered Therapeutics Section, Department of Advanced Organ Bioengineering and Therapeutics, Technical Medical Centre, University of Twente, 7500AE Enschede, The Netherlands.
Trends in Biotechnology
|December 26, 2021
Abstract:
Endotoxins are commonly present in both naturally derived and synthetic biomaterials. This Forum highlights the consequences of endotoxin contamination in biomaterials on different engineered tissues, such as bone, skin, or cartilage, and discusses the potential effects on novel 3D immunocompetent pathophysiological models.
