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Updated: Oct 8, 2025

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Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
Published on: October 20, 2021
3.4K
Technical advances in nerve-sparing and continence preservation.
Adriana M Pedraza1, Vinayak Wagaskar, Sneha Parekh
1Department of Urology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Current Opinion in Urology
|December 26, 2021
Summary
New surgical techniques aim to improve urinary continence and nerve sparing after radical prostatectomy. Advances focus on preservation, intraoperative assessment, and neural regeneration for better patient outcomes.
Area of Science:
- Urology
- Surgical Oncology
Background:
- Radical prostatectomy frequently leads to urinary incontinence and erectile dysfunction, significantly impacting quality of life.
- Optimizing trifecta outcomes (continence, potency, and cancer control) is a key goal in prostate cancer surgery.
Purpose of the Study:
- To review recent advances in surgical techniques and technology for nerve-sparing (NS) radical prostatectomy.
- To focus on strategies for preserving urinary continence (UC) and erectile function post-surgery.
Main Methods:
- Review of novel surgical techniques emphasizing preservation over reconstruction.
- Discussion of intraoperative assessment tools for prostatic and periprostatic structures.
- Exploration of neural regeneration strategies for functional recovery.
Main Results:
- New techniques enhance urinary continence and nerve sparing.
- Intraoperative assessment aids in nerve preservation while avoiding positive surgical margins (extracapsular extension - ECE).
- Neural regeneration research shows promise for improving erectile function and continence.
Conclusions:
- Achieving excellent outcomes in robot-assisted radical prostatectomy necessitates balancing nerve sparing with the risk of ECE.
- Thorough anatomical understanding and meticulous surgical planning are crucial for personalized patient approaches.

