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Updated: Oct 8, 2025

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
Published on: September 8, 2023
CoV-Spectrum: analysis of globally shared SARS-CoV-2 data to identify and characterize new variants
Chaoran Chen1,2, Sarah Nadeau1,2, Michael Yared3
1Department of Biosystems Science and Engineering, ETH Zürich, CH-4058 Basel, Switzerland.
Summary:
The CoV-Spectrum website supports the identification of new SARS-CoV-2 variants of concern and the tracking of known variants. Its flexible amino acid and nucleotide mutation search allows querying of variants before they are designated by a lineage nomenclature system. The platform brings together SARS-CoV-2 data from different sources and applies analyses. Results include the proportion of different variants over time, their demographic and geographic distributions, common mutations, hospitalization and mortality probabilities, estimates for transmission fitness advantage and insights obtained from wastewater samples.
Availability And Implementation:
CoV-Spectrum is available at https://cov-spectrum.org. The code is released under the GPL-3.0 license at https://github.com/cevo-public/cov-spectrum-website.
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