Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Sample Preparation for Analysis: Overview

Sample Preparation for Analysis: Overview

Sample preparation is an essential step in the analytical process. It involves preparing a sample so that it can be analyzed accurately. The goal is to extract the analyte, the substance you want to measure, from the sample while removing any components that may interfere with the analysis. Sample preparation techniques vary depending on the physical state of the sample.
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pyridines in food samples: Recent updates on pretreatment and analytical methods.

Journal of chromatography. A·2026

Same author

Extraction and determination of sartans: Recent advances and analytical perspectives.

Journal of pharmaceutical analysis·2026

Same author

Phenylurea herbicides in the environment: Recent updates on occurrence, distribution, risk assessment, and removal techniques.

Ecotoxicology and environmental safety·2026

Same author

A review of pretreatment and analytical methods for triphenylmethane dyes in environmental samples.

Journal of chromatography. A·2026

Same author

Non-negligible aldehydes in the environment: Emerging challenges and advanced removal strategies.

Ecotoxicology and environmental safety·2026

Same author

Emerging microextraction platforms for enhanced phthalic acid esters monitoring in food.

Food chemistry·2026

Search research articles

Related Experiment Video

Updated: Oct 8, 2025

Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies

Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies

Published on: April 12, 2022

Nicotine in Complex Samples: Recent Updates on the Pretreatment and Analysis Method.

Xin-Yue Tao^1,2, Yuan Zhang¹, Yu Zhou³

¹School of Pharmacy, China Medical University, Shenyang, China.

Critical Reviews in Analytical Chemistry

|December 27, 2021

Summary

This summary is machine-generated.

Accurate nicotine detection is crucial for tobacco product quality and public health. This review covers advanced sample preparation and analytical methods for precise nicotine quantification since 2015.

Keywords:

Analysis complex matrix nicotine pretreatment update

More Related Videos

A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

Published on: January 18, 2018

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Published on: January 10, 2015

Related Experiment Videos

Last Updated: Oct 8, 2025

Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies

Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies

Published on: April 12, 2022

A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

Published on: January 18, 2018

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Published on: January 10, 2015

Area of Science:

Analytical Chemistry
Forensic Science
Environmental Science

Background:

Nicotine is a key indicator of tobacco product quality.
Nicotine overdose presents significant health risks, including addiction and dependence.
Efficient and precise nicotine detection methods are essential for diverse samples and complex matrices.

Purpose of the Study:

To provide an updated summary of recent trends in nicotine pretreatment and analytical techniques.
To focus on developments in nicotine detection methods since 2015.
To discuss the applications, applicability, and future prospects of these techniques.

Main Methods:

Sample pretreatment methods reviewed include solid phase extraction, solid phase microextraction, liquid phase microextraction, and QuEChERS.
Analytical techniques discussed encompass liquid chromatography, gas chromatography, and electrochemical sensors.
Emphasis is placed on advancements in microextraction, automation, novel materials, ion sources, and mass analyzers.

Main Results:

A systematic summary of updated pretreatment and analysis methods for nicotine.
Microextraction and automation are identified as key trends in nicotine sample pretreatment.
Novel materials have significantly enhanced nicotine pretreatment techniques.

Conclusions:

The review highlights the latest advancements in nicotine detection methodologies.
Future developments are expected to focus on further refinement of microextraction, automation, and novel material applications.
Enhanced analytical instrumentation, particularly in ion sources and mass analyzers, will improve nicotine detection capabilities.