Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A novel scoring system for the prediction of disease severity in STEC-HUS.

Pediatrics international : official journal of the Japan Pediatric Society·2024

Same author

Ring formation by <i>Vibrio</i> fusion protein composed of FliF and FliG, MS-ring and C-ring component of bacterial flagellar motor in membrane.

Biophysics and physicobiology·2024

Same author

A Case of Nonalcoholic Steatohepatitis in Central Precocious Puberty Aggravated by Gonadotropin-releasing Hormone Analog.

JPGN reports·2023

Same author

Possible Paternal Hepatitis B Virus Infection with Different Clinical Courses between Siblings: A Report of Two Cases.

Case reports in hepatology·2022

Same author

Role of the N- and C-terminal regions of FliF, the MS ring component in <i>Vibrio</i> flagellar basal body.

Journal of bacteriology·2021

Same author

Refeeding syndrome in a 12-year-old girl with distal renal tubular acidosis.

Clinical case reports·2020

Search research articles

Related Experiment Video

Updated: Oct 8, 2025

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

Granulomonocytapheresis Using the Single-Needle Method for a Girl with Ulcerative Colitis.

Yoshiaki Sasaki¹, Hiroki Kajino¹

¹Department of Pediatrics, Abashiri-Kosei General Hospital, Abashiri City, Hokkaido, Japan.

Case Reports in Medicine

|December 27, 2021

Summary

Granulomonocytapheresis (GMA) effectively treats ulcerative colitis (UC) with few side effects. A single-needle method made pediatric GMA feasible, requiring only one blood vessel access.

More Related Videos

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Published on: September 26, 2019

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Related Experiment Videos

Last Updated: Oct 8, 2025

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Published on: September 26, 2019

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Area of Science:

Gastroenterology
Pediatric Gastroenterology
Apheresis Techniques

Background:

Refractory ulcerative colitis (UC) poses treatment challenges, particularly in pediatric patients.
Granulomonocytapheresis (GMA) is an established, drug-sparing therapy for inducing UC remission.
Standard GMA typically requires dual vascular access, complicating its use in children.

Observation:

A novel single-needle granulomonocytapheresis (GMA) approach was utilized in a pediatric UC patient.
This method involved securing only one blood vessel for the apheresis procedure.
The single-needle GMA was successfully administered 10 times without reported adverse events.

Findings:

The single-needle method proved to be a feasible alternative for GMA in a pediatric UC case.
This technique simplified vascular access, addressing a key challenge in pediatric apheresis.
No side effects were observed during the multiple treatment sessions.

Implications:

The single-needle GMA approach may expand the accessibility of this therapy for pediatric UC patients.
This modification could reduce procedural complexity and improve patient tolerance.
Further research into the single-needle method's efficacy and safety in pediatric populations is warranted.