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Analysis of quantitative and semi-quantitative parameters of DCE-MRI in differential diagnosis of benign and
Jun Song1, Yong Gu2, Tingting Du1
1Department of Radiology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China Mianyang, Sichuan, China.
Objective:
To explore and analyze the value of quantitative and semi-quantitative parameters of dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) in the differential diagnosis of benign and malignant cervical tumors.
Methods:
A total of 51 patients with cervical tumor who were treated in our hospital from April 2017 to October 2019 were recruited as the research subjects. All patients underwent conventional MRI plain scan and DCE-MRI examination. With histopathological results as the gold standard, the participants were classified into a malignant tumor group (n = 36) and a benign tumor group (n = 15) on the basis of the nature of the cervical tumor. The difference of quantitative and semi-quantitative parameters of DCE-MRI between the two groups was compared, and the specificity, sensitivity, negative and positive predictive values of quantitative and semi-quantitative parameters in differentiating benign from malignant cervical tumors were analyzed to evaluate the value of quantitative and semi-quantitative parameters of DCE-MRI in the differential diagnosis of benign and malignant cervical tumors.
Results:
The quantitative parameters Kep, Ktrans and Ve of DCE-MRI in the malignant-tumor-group were critically higher than that in the benign tumor group (P<0.05). When distinguishing between the benign and malignant cervical tumors, the specificity and sensitivity of kep, Ktrans and Ve were higher in the differential diagnosis of malignant cervical tumors than in the benign cervical tumors. The peak of the malignant tumor group was remarkably earlier than that of the benign tumor group, and SI60% of the malignant tumor group was dramatically higher than that of benign tumor group (P<0.05). In addition, compared with benign cervical tumors, the semi-quantitative parameters of DCE-MR TTP and SI60% were more sensitive to malignant cervical tumors.
Conclusion:
The quantitative and semi-quantitative parameters of DCE-MRI have high value in differentiating benign and malignant cervical tumors. When adopting conventional MRI to diagnose oncologic cervical tumors, the differential diagnosis of quantitative and semi-quantitative parameters of DCE-MRI has demonstrated a high clinical value by avoiding unnecessary radical surgeries.
