Study on biomechanical analysis of two-level cervical Mobi-C and arthrodesis

To investigate the range of motion (ROM) index of a two-level cervical arthroplasty.

Seven human cadaveric spines were biomechanically examined from C2 level to T1 level under intact status and the following conditions: 2-level arthroplasty (C4-C6) employing Mobi-C devices (MM group), 2-level anterior cervical discectomy and fusions (2-ACDFs) (FF group), and both as a hybrid surgery (HS) (MF group and FM group). Multidirectional flexibility examination was conducted according to the Panjabi hybrid testing protocol. Unconstrained intact moments of ±1.5 NM were performed for axial rotation (AR) flexion/extension (FE), and lateral bending (LB).

No statistical differences were found between the intact spine and MM group at the operative- and adjacent-level kinematics in the three loading conditions, except that C4-C5 ROM significantly increased in the axial rotation loading (P<0.05). Compared with the intact spine, MF group led to a significant decrease at the arthrodesis segment ROM C5-C6 in the three loading (P<0.05), with corresponding significantly increased at C4-C5 in FE and AR (P<0.05). FM group resulted in a significant decrease in ROM C4-C5 (P<0.05) with corresponding significantly increased at C5-C6 in FE, AR and LB (P<0.05). There was not any difference for non-operative level kinematics between MF group and FM group and intact spine. Compared with the intact spine, FF group led to a significant decrease at the arthrodesis-levels (P<0.05) and marked increase at the non-operative level kinematics.

A two-level Mobi-C and Hybrid construct generated better biomechanical conditions. This study suggested that two-level cervical total disc replacement or HS could become an alternative approach for therapy of two-level consecutive cervical spondylosis.