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Intralymphatic Immunotherapy and Vaccination in Mice
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The toxicity of recombinant human interleukin-2 in rats following intravenous infusion

Y L Matory, A E Chang, E H Lipford

    Journal of the National Medical Association
    |May 1, 1987
    PubMed

    Abstract:

    Studies of recombinant interleukin-2 (RIL-2) administered by continuous intravenous infusion revealed hepatocellular toxicity and redistribution of lymphoid cells. This finding was different from the normal findings seen in rats receiving comparable infusions of the vehicle.

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