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Agreement and Repeatability of Central and Peripheral Refraction by One Novel Multispectral-Based Refractor
Weicong Lu1, Rongyuan Ji1, Wenzhi Ding1
1State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University, Qingdao, China.
Frontiers in Medicine
|December 27, 2021
Summary
Multispectral refractive tomography shows high repeatability for central and peripheral myopia measurements. Peripheral nasal, temporal, superior, and inferior measurements were less precise than central ones.
Area of Science:
- Ophthalmology
- Optometry
- Optical Engineering
Background:
- Accurate refractive error measurement is crucial for myopia management.
- Evaluating new technologies for precise central and peripheral refraction is an ongoing need.
- Multispectral refractive tomography (MRT) offers a novel approach to objective refraction.
Purpose of the Study:
- To assess the repeatability of a multispectral refractor for central and peripheral myopia.
- To compare MRT measurements with objective refraction (OR) and subjective refraction (SR).
Main Methods:
- Prospective study of 60 myopic patients across three refractive error groups.
- Central and peripheral refraction measured using MRT pre- and post-cycloplegia.
- Intraobserver repeatability analyzed via Sw, TRT, and ICC; agreement assessed using Bland-Altman plots and 95% LoA.
Main Results:
- High intraobserver repeatability (ICC > 0.97) for central and peripheral refraction.
- Peripheral nasal, temporal, superior, and inferior quadrants showed larger error intervals (up to 1.43 D).
- 95% LoA between MRT and OR/SR ranged from -1.39 D to 1.16 D, varying with cycloplegia.
Conclusions:
- Multispectral refractive tomography demonstrates good repeatability for myopia assessment.
- Peripheral refraction measurements in specific quadrants require further refinement.
- The technology shows promise for objective and repeatable refractive error evaluation.

