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Data sources for drug utilization research in Latin American countries-A cross-national study: DASDUR-LATAM study
Luciane C Lopes1, Maribel Salas2,3, Claudia Garcia Serpa Osorio-de-Castro4
1Pharmaceutical Science Graduate Course, University of Sorocaba, Sorocaba, Brazil.
Drug utilization research (DUR) in Latin America faces data accessibility challenges. This study identified 125 potential data sources, but many have limited or no public access, hindering health system strengthening.
Area of Science:
- Health Services Research
- Pharmacoepidemiology
- Health Policy
Background:
- Drug utilization research (DUR) is crucial for informing health policy and strengthening health systems.
- Systematized information on DUR data sources in Latin American (LatAm) countries is lacking.
- Identifying and characterizing available data sources is a prerequisite for conducting DUR.
Purpose of the Study:
- To compile and characterize potential data sources for drug utilization research in Latin American countries.
- To assess the availability and accessibility of these data sources.
Main Methods:
- A network of DUR experts from nine Latin American countries was established.
- Data sources were identified through website searches of governmental, academic, and private health institutions.
- Data sources were screened and characterized based on accessibility, geographic granularity, setting, sector, source, and data type, with input from national pharmacoepidemiology experts via an online survey.
Main Results:
- A total of 125 potential data sources for DUR were identified across nine Latin American countries.
- Only 38% (30%) of these sources were publicly and conveniently available; 71% had limited accessibility, and 14% were inaccessible.
- The majority of sources were from the public sector (61%), with a significant portion from pharmacy records (37%), and 68% provided individual patient-level data.
Conclusions:
- Despite the availability of numerous data sources for DUR in Latin America, accessibility remains a significant barrier.
- Transparent, feasible, affordable, and protocol-driven procedures are needed for accessing DUR data.
- This inventory facilitates cross-country comparisons of drug utilization, potentially identifying medication-related problems for further investigation.
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Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...

