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Engineering Antiviral Agents via Surface Plasmon Resonance
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Silver Nanoparticles as Potential Antiviral Agents.

Zubair Ahmed Ratan1,2, Fazla Rabbi Mashrur1, Anisha Parsub Chhoan1

  • 1Department of Biomedical Engineering, Khulna University of Engineering & Technology, Khulna 9203, Bangladesh.

Pharmaceutics
|December 28, 2021
PubMed
Summary
This summary is machine-generated.

Silver nanoparticles (AgNPs) show promise as antiviral agents against emerging viral infections. This review explores AgNPs' properties, antiviral mechanisms, and applications, highlighting their potential in nanomedicine.

Keywords:
antiviral activitysilver nanoparticlesviral infectionvirus

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Area of Science:

  • Nanomedicine
  • Biotechnology
  • Material Science

Background:

  • Emerging viral infections pose significant global health and economic threats.
  • Developing effective antiviral therapies is challenging due to viral reliance on host cells for replication.
  • Silver nanoparticles (AgNPs) demonstrate broad antimicrobial potential against viruses, bacteria, and fungi.

Purpose of the Study:

  • To review the potential of silver nanoparticles (AgNPs) as antiviral agents.
  • To discuss the characterization, antiviral activity, mechanisms, applications, and toxicity of AgNPs.

Main Methods:

  • Literature review focusing on studies evaluating the antiviral properties of AgNPs.
  • Analysis of AgNP characterization techniques.
  • Examination of reported antiviral mechanisms and applications.
  • Assessment of AgNP toxicity.

Main Results:

  • AgNPs exhibit diverse mechanisms for disrupting viral infectivity and replication.
  • Various characterization methods confirm AgNP properties relevant to antiviral action.
  • Potential applications span from direct therapeutic use to surface disinfection.
  • Toxicity profiles require careful consideration for safe clinical translation.

Conclusions:

  • Silver nanoparticles represent a promising platform for developing novel antiviral strategies.
  • Further research into AgNP mechanisms and safety is crucial for clinical application in nanomedicine.
  • AgNPs offer a versatile approach to combatting viral threats, including emerging infectious diseases.