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Monomer Elution from Three Resin Composites at Two Different Time Interval Using High Performance Liquid
Krishnamachari Janani1, Kavalipurapu Venkata Teja2, Raghu Sandhya2
1SRM Institute of Science and Technology, SRM Dental College, Chennai 600089, Tamil Nadu, India.
Polymers
|December 28, 2021
Summary
Monomer elution from dental resin composites was quantified. Bisphenol A-glycidyl methacrylate (Bis-GMA) and Triethylene glycol dimethacrylate (TEGDMA) were detected, indicating potential concerns for routine clinical practice.
Area of Science:
- Dental Materials Science
- Polymer Chemistry
- Analytical Chemistry
Background:
- Photo-activated resin composites are widely used in dentistry for restorations.
- Inadequate polymerization may lead to monomer elution, raising potential health concerns.
- Understanding monomer release is crucial for assessing the safety and longevity of dental materials.
Purpose of the Study:
- To quantify the elution of monomers from three different resin composite materials.
- To identify specific monomers released and their quantities over time.
- To evaluate potential differences in monomer elution between various composite formulations.
Main Methods:
- Three resin composite materials (Swiss Tech, Ceram X, Beautifil Injectable) were tested.
- Cylindrical samples were immersed in 75% ethanol and stored at room temperature.
- High-performance liquid chromatography (HPLC) was used to quantify Bisphenol A-glycidyl methacrylate (Bis-GMA), Triethylene glycol dimethacrylate (TEGDMA), 2-hydroxyethyl methacrylate (HEMA), and Urethane dimethacrylate (UDMA) at 24 hours and 7 days.
Main Results:
- At 24 hours, Bis-GMA eluted most from the injectable composite, while TEGDMA eluted from Swiss Tech and Ceram X.
- By the 7th day, Bis-GMA showed the highest elution across all three resin composites.
- Significant monomer release was detected from all tested resin composite materials.
Conclusions:
- Monomer elution is evident from the tested resin composites.
- The type and quantity of eluted monomers vary between materials and over time.
- Regular assessment of monomer release is important in routine dental clinical practice.

