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Does the initial chest radiograph severity in COVID-19 impact the short- and long-term outcome? - a perspective from

Maria M D'souza1, Aruna Kaushik1, Jeanne Maria Dsouza2

  • 1Institute of Nuclear Medicine and Allied Sciences, Delhi, India.

Infectious Diseases (London, England)
|December 28, 2021
PubMed

Insights

Chest X-rays (CXRs) predict COVID-19 outcomes. Higher CXR scores correlate with severe disease, mortality, and long-term symptoms, guiding patient management.

Area of Science:

  • Radiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Chest radiography (CXR) is a common diagnostic tool for COVID-19.
  • The predictive value of CXR for long-term COVID-19 outcomes remains unclear.

Purpose of the Study:

  • To investigate the association between baseline CXR findings and short-term and long-term outcomes in COVID-19 patients.

Main Methods:

  • 1530 COVID-19 patients had baseline CXRs analyzed for lesion patterns.
  • The Brixia scoring system quantified radiographic severity.
  • Short-term outcomes included clinical severity, hospitalization duration, and mortality.
  • Survivors were assessed for residual symptoms at 5-6 months.

Main Results:

  • 67% of patients had abnormal CXRs, often showing bilateral, basal ground-glass opacities.
  • The median Brixia score was 2 (IQR [0-6]).
  • 36% of survivors reported residual symptoms at follow-up.
  • CXR scores correlated with disease severity and hospitalization duration.
  • CXR scores independently predicted mortality and long-term symptoms.

Conclusions:

  • Chest radiograph severity predicts both short-term and long-term consequences of COVID-19.
  • CXR findings can serve as a prognostic indicator for patient management and follow-up.
Abstract

Keywords:
COVID-19chest radiographlong-term outcomeshort-term outcome

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