Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative performance of biopolymer-supported graphitic carbon nitride nanosheets for electrochemical carcinoembryonic antigen cancer biomarker detection in serum samples using smartphone device.

Mikrochimica acta·2026
Same author

Surface-Engineered Smart Carbon Quantum Dots at the Brain Interface for Neurotherapeutics and Brain Imaging: From Surface to Synapse.

Analytical chemistry·2026
Same author

Tympanoplsty with or without mastoidectmy is highly effective treatment of chronic otitis media in padiatric age group.

International journal of pediatric otorhinolaryngology·2026
Same author

Biomaterials and Nanoparticle-Based Therapeutics in Neurodegenerative Diseases: Bridging the Gap Between Innovation and Translation.

ACS chemical neuroscience·2026
Same author

Detection and Utilisation of KASPar SNP Marker Assays for Early Blight Resistance in Tomato.

Current microbiology·2026
Same author

Transformer-based embeddings and stacking classifiers for judgment outcome prediction in multilingual legal texts.

Scientific reports·2026

Related Experiment Video

Updated: Oct 8, 2025

Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor
09:33

Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor

Published on: March 21, 2018

10.0K

2D Materials-Based Aptamer Biosensors: Present Status and Way Forward.

Raj Kumar Sen1,2, Priyanka Prabhakar1,2, Neha Bisht1

  • 1CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal 462026, India.

Current Medicinal Chemistry
|December 28, 2021
PubMed
Summary

This review highlights two-dimensional materials (2DMs) as promising components for aptasensors. These nanomaterials offer unique properties for advanced diagnostic applications like pathogen and protein detection.

Keywords:
2D materialAptamerbiosensordiagnosisgraphenemxene

More Related Videos

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

15.3K
Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

6.8K

Related Experiment Videos

Last Updated: Oct 8, 2025

Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor
09:33

Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor

Published on: March 21, 2018

10.0K
A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

15.3K
Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

6.8K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biosensing

Background:

  • Two-dimensional materials (2DMs) possess unique physicochemical, optical, and electronic properties.
  • Their high surface-to-volume ratio, adjustable functionality, and multivalent structure are ideal for biosensor development.
  • Diverse 2DMs including graphene, MXenes, and transition metal dichalcogenides show significant potential.

Purpose of the Study:

  • To review the potential of 2D material-based aptasensors for diagnostic applications.
  • To explore the integration of various 2DMs with aptamers for enhanced biosensing capabilities.
  • To discuss applications in protein detection, environmental monitoring, and pathogen identification.

Main Methods:

  • Review of current literature on 2D materials and aptasensor fabrication.
  • Analysis of binding interactions between 2DMs and aptamers (covalent, non-covalent, hydrogen bonding, π-stacking).
  • Evaluation of 2DMs for diagnostic applications based on their properties and aptamer conjugation.

Main Results:

  • 2DMs offer excellent platforms for aptasensor development due to their inherent properties.
  • Aptamers provide high specificity and affinity, crucial for accurate diagnostics.
  • The combination of 2DMs and aptamers leads to enhanced biosensing performance.

Conclusions:

  • 2D material-based aptasensors represent a significant advancement in diagnostic technology.
  • These sensors show great promise for sensitive and specific detection in various fields.
  • Further research into novel 2DMs and aptamer designs will expand their diagnostic utility.