Lattice dystrophy of the cornea: a clinicopathological case report

The clinical and pathological corneal findings in a patient with lattice dystrophy of the cornea type I are presented. Amyloid, the corneal stromal deposit in this dystrophy, has been shown to be heterogeneous by means of immunohistochemical techniques despite uniform ultrastructural features. The possible sources of amyloid include leakage from serum, extracellular breakdown of corneal collagen and, most probably, localized intracellular production.