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Cardiac Output I:Effect of Heart Rate on Cardiac Output01:19

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Cardiorespiratory kinetics in exercise physiology: estimates and predictions using randomized changes in work rate.

Uwe Hoffmann1, Felix Faber2, Uwe Drescher2

  • 1Department of Exercise Physiology, Institute of Exercise Training and Sport Informatics, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933, Cologne, Germany. u.hoffmann@dshs-koeln.de.

European Journal of Applied Physiology
|December 28, 2021
PubMed
Summary
This summary is machine-generated.

Pseudo-random binary sequence (PRBS) testing effectively models cardiorespiratory parameter (CRP) kinetics during exercise. This method accurately predicts steady states and responses to incremental exercise intensity changes.

Keywords:
Exercise testingKineticsPRBSPrediction

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Area of Science:

  • Exercise Physiology
  • Cardiorespiratory Function
  • Systems Physiology

Background:

  • Cardiorespiratory parameter (CRP) kinetics are crucial for understanding exercise responses.
  • Pseudo-random binary sequence (PRBS) testing offers a dynamic method to assess these kinetics.
  • Predicting steady-state and incremental exercise responses is vital for exercise prescription and clinical assessment.

Purpose of the Study:

  • To evaluate the kinetics of cardiorespiratory parameters (CRP) using pseudo-random binary sequence (PRBS) testing.
  • To apply two algorithms for converting PRBS responses into impulse responses.
  • To predict steady-state values and responses to incremental exercise intensity.

Main Methods:

  • 13 participants underwent an exercise test protocol including PRBS, constant work rate, and incremental stages.
  • Ventilation, O2 uptake, CO2 output, and heart rate were continuously monitored.
  • Impulse responses were calculated in the time and frequency domains using cross-correlations.

Main Results:

  • The time-domain algorithm provided better predictions for O2 uptake and CO2 output.
  • Both algorithms yielded similar results for ventilation and heart rate.
  • Accurate predictions for O2 uptake and heart rate were achieved, with minor deviations at different work rates.

Conclusions:

  • CRP kinetics derived from PRBS testing are suitable for assessing steady states within the tested work rate range.
  • The model sufficiently predicts ventilation and heart rate responses to incremental exercise below the ventilatory threshold.