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Related Concept Videos

Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...

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Association Between Skin Findings and Ocular Signs in Rosacea.

Francisco Lucero Saá1, Federico Cremona1, Pablo Chiaradia1

  • 1Hospital de Clínicas José de San Martin, Universidad de Buenos Aires (UBA), Department of Ophthalmology, Buenos Aires, Arjantin.

Turkish Journal of Ophthalmology
|December 29, 2021
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Summary

Ocular rosacea affects over 70% of patients, with lid margin erythema and meibomian gland dysfunction being most common. Severe ocular findings correlate with specific skin symptoms like papules and pustules.

Keywords:
Rosaceadry eye diseaseocular cicatricial pemphigoidocular rosaceaocular surface disease

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Area of Science:

  • Ophthalmology
  • Dermatology
  • Immunopathology

Background:

  • Ocular rosacea is a common condition affecting the eyes.
  • Understanding the prevalence and specific signs of ocular rosacea is crucial for patient management.
  • The association between ocular and dermatological manifestations requires further investigation.

Purpose of the Study:

  • To identify the most frequent ocular signs in patients with rosacea.
  • To assess the correlation between ocular findings and cutaneous manifestations of rosacea.
  • To investigate the coexistence of rosacea with other ocular conditions like ocular cicatricial pemphigoid (OCP).

Main Methods:

  • Fifty-one patients diagnosed with rosacea underwent comprehensive ophthalmological examinations.
  • Ocular surface specialists evaluated patients for specific signs and symptoms.
  • Immunohistopathological analysis was performed on conjunctival specimens in select cases.

Main Results:

  • Ocular signs were present in 74.5% of rosacea patients, with lid margin erythema, meibomian gland dysfunction, and blepharitis being most prevalent.
  • Decreased visual acuity occurred in 15 patients due to complications like leukoma and corneal neovascularization.
  • Lower visual acuity was significantly associated with dermatological signs of papules/pustules and rhinophyma. Two patients were diagnosed with OCP.

Conclusions:

  • Ocular involvement is highly prevalent in rosacea patients.
  • A potential relationship exists between the severity of ocular compromise and specific cutaneous subtypes of rosacea.
  • Rosacea and OCP can coexist, and biopsy is essential for diagnosing conjunctival fibrotic changes.