Chemical Pleurodesis Using a Viscum album Extract in an Infant with Postoperative Chylothorax: A Case Report

Taeyoung Yun1, Hye Won Kwon1, Samina Park1

  • 1Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Journal of Chest Surgery
|December 29, 2021
PubMed

Insights

Refractory chylothorax in infants post-cardiothoracic surgery can be challenging. Chemical pleurodesis using a Viscum album extract offers a successful treatment option, preventing recurrence.

Area of Science:

  • Thoracic Surgery
  • Pediatric Cardiology
  • Pleural Medicine

Background:

  • Chylothorax is a rare but serious complication following cardiothoracic surgery.
  • Refractory cases pose significant treatment challenges, often requiring invasive interventions.
  • Infantile chylothorax necessitates specialized management strategies.

Observation:

  • A case of post-cardiothoracic surgery chylothorax in an infant is presented.
  • The infant failed to respond to conservative management and thoracic duct ligation.
  • This highlights the need for alternative therapeutic approaches.

Findings:

  • Chemical pleurodesis was performed using a Viscum album extract.
  • The treatment resulted in successful resolution of the chylothorax.
  • No recurrence of chylothorax was observed post-treatment.

Implications:

  • Viscum album extract represents a potential novel therapeutic agent for refractory chylothorax.
  • This case suggests a promising, less invasive option for managing complex pediatric pleural effusions.
  • Further research into Viscum album for treating chylothorax is warranted.

Related Concept Videos

Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
317
Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
441
Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
2.2K
Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
610
Chest Physiotherapy01:24

Chest Physiotherapy

Chest Physiotherapy (CPT) is a therapeutic technique used in respiratory care to improve ventilation, clear bronchial secretions, and enhance the efficiency of respiratory muscles. This therapy includes three primary procedures: postural drainage, percussion, and vibration. It can be performed on spontaneously breathing patients and those who are intubated and mechanically ventilated.
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
870
Flail Chest-II01:26

Flail Chest-II

Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
278