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Updated: Oct 8, 2025

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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report
Hiroshi Sato1, Seiki Matsuo1, Yukiko Ando1
1Department of Clinical Genetics Hyogo Prefectural Amagasaki General Medical Center Amagasaki Japan.
Clinical Case Reports
|December 29, 2021
Abstract:
TP53 mutations in acute myeloid leukemia (AML) are associated with poor outcomes. The number of somatic and/or germline genetic tests for therapy is increasing. Patients with such incidental findings should undergo adequate genetic counseling.

