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Septic Portal Vein Thrombosis, Clinical Presentation, and Management

Simran Anand1,2, Chukwuemeka A Umeh2, Curren Giberson2

  • 1Internal Medicine, St. George's University School of Medicine, True Blue, GRD.

Cureus
|December 29, 2021
PubMed

Insights

Pylephlebitis, or septic portal vein thrombosis, is an infection of the portal vein. Early diagnosis and antibiotic treatment are crucial for managing this often-missed condition.

Area of Science:

  • Internal Medicine
  • Radiology
  • Infectious Diseases

Background:

  • Pylephlebitis, or septic portal vein thrombosis, involves infective, suppurative thrombosis of the portal vein and its intra-hepatic branches.
  • It is a serious condition that can be challenging to diagnose but is treatable with antibiotics.

Observation:

  • This case report details a patient presenting with symptoms suggestive of pylephlebitis.
  • Key clinical signs included fever, abdominal pain, and leukocytosis.
  • Imaging revealed evidence of portal vein thrombosis on a CT scan.

Findings:

  • The case highlights the importance of considering pylephlebitis in patients with the aforementioned clinical presentation and imaging findings.
  • Septic portal vein thrombosis, though often overlooked, is a treatable diagnosis.

Implications:

  • Early consideration of pylephlebitis can lead to prompt diagnosis and effective antibiotic therapy.
  • This emphasizes the need for integrating clinical suspicion with radiological evidence for timely management of septic portal vein thrombosis.
Keywords:
hepatic abscesshypercoagulopathypylephlebitisseptic portal vein thrombosissuperior mesenteric vein thrombosis

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