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[Poppers maculopathy (case study)].

N V Zhorzholadze1, N L Sheremet1, T V Smirnova1

  • 1Research Institute of Eye Diseases, Moscow, Russia.

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|December 29, 2021
PubMed
Summary

This case study details poppers-associated maculopathy, a rare toxic retinal disorder. Complete cessation of poppers use is the primary treatment strategy for affected individuals.

Keywords:
electroretinographymaculopathyoptical coherence tomographypoppers maculopathystatic perimetry

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Area of Science:

  • Ophthalmology
  • Toxicology

Background:

  • Poppers-associated maculopathy is a toxic optic neuropathy.
  • This condition is rarely documented in Russian scientific literature.

Purpose of the Study:

  • To present a clinical case of poppers-associated maculopathy.
  • To highlight diagnostic methods and treatment strategies for this condition.

Main Methods:

  • Diagnosis based on patient history of long-term poppers use.
  • Spectral optical coherence tomography (OCT) to identify retinal structural changes.
  • Multifocal and ganzfeld electroretinography (ERG) to assess retinal function.

Main Results:

  • Confirmed diagnosis of toxic maculopathy linked to alkyl nitrite (poppers) use.
  • OCT revealed specific structural damage in the outer retinal layers of the foveolar zone.
  • ERG showed characteristic functional abnormalities.

Conclusions:

  • Complete cessation of poppers is the essential treatment for poppers-associated maculopathy.
  • Early diagnosis and intervention are crucial for managing this toxic retinal disorder.