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Updated: Oct 8, 2025

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Initiative to Improve Postintubation Sedation in a Pediatric Emergency Department
Insights
Implementing an intubation checklist and a multidisciplinary approach significantly improved timely pediatric postintubation sedation (PIS), increasing adequate PIS rates by over 27% and reducing variability.
Area of Science:
- Pediatric Critical Care Medicine
- Patient Safety
- Quality Improvement Initiatives
Background:
- Appropriate pediatric postintubation sedation (PIS) after rapid sequence intubation (RSI) is administered in only 28% of cases.
- High provider variability, cognitive overload, and errors of omission contribute to delays in PIS for paralyzed pediatric patients.
Purpose of the Study:
- To enhance the proportion of children receiving timely PIS by 20% within a 6-month period.
Main Methods:
- A multidisciplinary team identified key drivers of PIS delay and implemented targeted interventions.
- Defined "adequate time frame" for PIS as sedative administration within the duration of action of the RSI sedative agent.
- Monitored primary and secondary outcomes, including the proportion of patients receiving any PIS and time to PIS administration.
Main Results:
- Adequate PIS improved from 27.9% to 55.6% (p = .001) post-intervention.
- The overall proportion of patients receiving any PIS increased from 74% to 94% (p = .006).
- Median time from RSI to PIS decreased from 13 to 9 minutes (p < .001), with reduced variability.
Conclusions:
- An intubation checklist and a multidisciplinary strategy effectively improved the rate of adequate pediatric PIS.
- These interventions successfully addressed delays and variability in PIS administration.
Background:
Previous research has shown that appropriate pediatric postintubation sedation (PIS) after rapid sequence intubation only occurs 28% of the time. Factors such as high provider variability, cognitive overload, and errors of omission can delay time to PIS in a paralyzed patient.
Purpose:
To increase the proportion of children receiving timely PIS by 20% within 6 months.
Methods:
A multidisciplinary team identified key drivers and targeted interventions to improve timeliness of PIS. The primary outcome of "sedation in an adequate time frame" was defined as a time to post-Rapid Sequence Intubation sedative administration less than the duration of action of the RSI sedative agent. Secondary outcomes included the proportion of patients receiving any sedation and time to PIS administration.
Results:
Pediatric postintubation sedation in an adequate time was improved from 27.9% of intubated patients to 55.6% after intervention (p = .001). The number of patients receiving any PIS improved from 74% to 94% (p = .006). The median time from RSI to PIS was reduced from 13 to 9 minutes (p < .001). Process control charts showed a reduction in PIS variability and a centerline reduction from 19 to 10 minutes.
Conclusions:
Implementation of an intubation checklist and a multidisciplinary approach improved the rate of adequate pediatric PIS.
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