Related Experiment Video
Updated: Oct 8, 2025

Author Spotlight: Exploring Light-Driven Chemical Reactions and Energy-Harnessing Devices in Photochemical Research
Published on: February 16, 2024
What is Interpretability?
Adrian Erasmus1,2, Tyler D P Brunet2, Eyal Fisher3
1Institute for the Future of Knowledge, University of Johannesburg, Johannesburg, South Africa.
Abstract:
We argue that artificial networks are explainable and offer a novel theory of interpretability. Two sets of conceptual questions are prominent in theoretical engagements with artificial neural networks, especially in the context of medical artificial intelligence: (1) Are networks explainable, and if so, what does it mean to explain the output of a network? And (2) what does it mean for a network to be interpretable? We argue that accounts of "explanation" tailored specifically to neural networks have ineffectively reinvented the wheel. In response to (1), we show how four familiar accounts of explanation apply to neural networks as they would to any scientific phenomenon. We diagnose the confusion about explaining neural networks within the machine learning literature as an equivocation on "explainability," "understandability" and "interpretability." To remedy this, we distinguish between these notions, and answer (2) by offering a theory and typology of interpretation in machine learning. Interpretation is something one does to an explanation with the aim of producing another, more understandable, explanation. As with explanation, there are various concepts and methods involved in interpretation: Total or Partial, Global or Local, and Approximative or Isomorphic. Our account of "interpretability" is consistent with uses in the machine learning literature, in keeping with the philosophy of explanation and understanding, and pays special attention to medical artificial intelligence systems.
More Related Videos
05:47Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
16:23Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction
Published on: February 26, 2014
Related Concept Videos
Bioequivalence Data: Statistical Interpretation
Biostatistics: Overview
Discrete variables are...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Uncertainty: Overview
Interpreting R Charts
An R chart plots the range of subsets of measurements collected from a process. Each point on the chart represents the range—defined as the difference between the maximum and minimum...
The Scientific Method
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...