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Prevention of Further Absorption of Poison

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In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...

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Enhanced Drainage Protocol in Large Amoebic Liver Abscess.

Jignesh A Gandhi¹, Pravin H Shinde², Sadashiv N Chaudhari²

¹Department of Surgery, Global Hospital Mumbai, Parel, Mumbai, India.

Surgery Journal (New York, N.Y.)

|December 30, 2021

Summary

This summary is machine-generated.

A large 24 French (Fr) drain significantly speeds up recovery for amebic liver abscess (ALA) patients compared to standard 10 Fr pigtail catheters. This wide-bore drain reduces hospital stay and symptom duration, improving outcomes for ALA management.

Keywords:

amoebic liver abscess biliary communication drain pigtail

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In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion

In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion

Published on: November 10, 2011

Area of Science:

Hepatology
Interventional Radiology
Infectious Diseases

Background:

Amebic liver abscess (ALA) is a major cause of illness and death in developing nations.
While medical treatment is primary, 15% of ALA cases are refractory and need drainage.
Standard pigtail catheterization is often inefficient, leading to prolonged hospital stays.

Purpose of the Study:

To compare the efficacy and safety of a wide-bore 24 French (Fr) drain versus a 10 Fr pigtail catheter for draining large amebic liver abscesses.
To evaluate the impact on clinical symptom resolution, hospital stay duration, and abscess clearance.

Main Methods:

A single-center, prospective observational study over 5 years included 122 patients with ALA.
Patients received empirical medical therapy followed by drainage using either a 10 Fr pigtail or a 24 Fr drain.
Primary outcomes included symptom resolution, length of hospital stay, and abscess resolution on imaging at day 3.

Main Results:

The 24 Fr drain group showed faster symptom resolution (2.4 vs. 5.1 days) and shorter catheter duration (6.4 vs. 13.2 days).
Abscess drainage was quicker with the 24 Fr drain, evidenced by less residual volume at day 3 (177 vs. 212 mL).
Alcoholics were more prone to developing large ALAs; 28 patients had biliary communication, with 26 requiring endoscopic retrograde cholangiopancreatography.

Conclusions:

A wide-bore 24 Fr drain accelerates patient recovery in large amebic liver abscesses compared to standard 10 Fr pigtail catheters.
Biliary stenting is a valuable adjunct for managing biliary communication, potentially avoiding major surgery.