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[Fosfomycin: potential and perspectives for use in urological practice]
A V Zaitsev1, I S Palagin2,3
1Department of Urology, Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Ministry of Health of the Russian Federation, Moscow, Russia.
Urologiia (Moscow, Russia : 1999)
|December 30, 2021
Summary
Multidrug-resistant infections pose a significant global health threat due to a lack of new antibiotics. Older antibiotics may offer new treatment options for resistant bacteria.
Area of Science:
- Microbiology
- Infectious Diseases
- Pharmacology
Background:
- Rising rates of multidrug-resistant (MDR) infections present a critical global health challenge.
- Antimicrobial resistance is recognized by the World Health Organization as a major threat to public health.
- A significant gap exists in the development of novel antibiotics effective against MDR bacteria.
Purpose of the Study:
- To highlight the critical issue of antimicrobial resistance and the urgent need for new therapeutic strategies.
- To explore the potential of repurposing existing antibiotics for new clinical indications.
Main Methods:
- Review of current literature on antimicrobial resistance trends.
- Analysis of the pipeline for new antibiotic development.
- Investigation into the potential for re-evaluation of established antibiotics.
Main Results:
- The increasing prevalence of multidrug-resistant microorganisms is a serious medical concern.
- The development of new antibiotics has not kept pace with the rise of resistance.
- Established antibiotics may be candidates for new therapeutic uses.
Conclusions:
- Addressing the threat of antimicrobial resistance requires a multifaceted approach.
- Repurposing "old" antibiotics could provide valuable new treatment options for MDR infections.
- Continued research into both novel and existing antimicrobial agents is essential.
Keywords:
Escherichia coliantibiotic resistanceefficacyfosfomycinsafetytherapyurinary tract infectionsMore Related Videos
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