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Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
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Related Experiment Video

Updated: Oct 8, 2025

A Mouse Distraction Osteogenesis Model
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Monobloc Differential Distraction Osteogenesis.

John W Polley1, Alvaro A Figueroa2, John A Girotto1

  • 1Department of Plastic and Dermatologic Surgery, Helen DeVos Children's Hospital, Grand Rapids, MI.

The Journal of Craniofacial Surgery
|December 30, 2021
PubMed
Summary
This summary is machine-generated.

Monobloc differential distraction osteogenesis safely advances the midface in syndromic craniosynostosis patients. This technique provides stable, long-term aesthetic and functional improvements, even in young children.

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Area of Science:

  • Craniofacial Surgery
  • Orthognathic Surgery
  • Pediatric Plastic Surgery

Background:

  • Monobloc reconstruction is crucial for craniofacial dysostosis, addressing functional and aesthetic deficits.
  • Distraction osteogenesis minimizes morbidity compared to traditional monobloc surgery.

Purpose of the Study:

  • To evaluate outcomes, stability, and growth after monobloc advancement in syndromic craniosynostosis patients.
  • To analyze results in skeletally immature patients treated with monobloc differential distraction osteogenesis.

Main Methods:

  • A consecutive series of thirty patients with craniofacial dysostosis underwent monobloc differential distraction osteogenesis.
  • Long-term radiographic and photographic data were reviewed, including a subset of skeletally immature patients.

Main Results:

  • Mean horizontal advancement was 12 mm at nasion and 10 mm at A-point.
  • At mean follow-up, positive horizontal changes of 1.1 mm (nasion) and 0.8 mm (A-point) were observed.
  • Younger patients (<7 years) demonstrated more pronounced positive horizontal changes.

Conclusions:

  • Monobloc differential distraction osteogenesis enables safe and precise midface repositioning.
  • The advancement is skeletally stable, with young patients exhibiting moderate continued growth.