The Gate-Modified Solution-Gated Graphene Transistors for the Highly Sensitive Detection of Lead Ions

Lead ions are heavy metal ions that are extremely harmful to the human body and ecological environment. They can cause irreversible damage to the human nervous system and blood system at low concentrations. It is very important to develop a simple, rapid, and sensitive detection method of Pb²⁺. Solution-gated graphene transistors (SGGTs) have been widely studied in recent years due to their ultra-high sensitivity in chemical sensing. Herein, we have demonstrated a sensitive sensor of Pb²⁺ based on the SGGTs through the glutathione gate modification. When Pb²⁺ are added into the electrolyte solution, the electrical double layer capacitance near the gate electrode changes because Pb²⁺ can be strongly chelated, leading to the channel current change. The detection of Pb²⁺ can be realized. The detection limit of sensors for Pb²⁺ can reach 1 × 10^-18 M, and the response time is about 1 s. The channel current change and the logarithm of Pb²⁺ concentration exhibit a good linear relationship in the concentration range of 1 × 10^-18 and 1 × 10^-6 M. Because the glutathione molecule can well recognize Pb²⁺, the devices also demonstrate good selectivity to Pb²⁺. Compared with the convention detection, our method shows easy operation, high sensitivity, and high selectivity. Therefore, it has great potential in the analysis of trace samples for health and environment monitoring.